william odette
Ph.D. Student |
Research projectInvestigation of redox active GUVs
The aim of this project is to investigate the use of unilamellar vesicles for drug delivery and other uses. The research focus mainly on Giant and Large unilamellar vesicles (GUVs and LUVs). We synthesized a novel type of redox active phospholipid that was used for the assembly new family of redox active vesicles the transport and payload release mechanism of vesicles is examined. Currently we are working on the development of a new family of PEGylated redox active phospholipids to enhance the drug delivery abilities of our system. We use advanced electrochemical and spectroscopic methods as well as in-vivo and in-vitro immunoarray methods to characterize our system and obtain a proof of concept. |
Publications
Odette, W.L.; Payne, N.A.; Khaliullin, R.Z.; Mauzeroll, J. Redox-Triggered Disassembly of Nanosize Liposomes Containing Ferrocene-Appended Amphiphiles. Langmuir 2019, 35, 5608-5616.
Danis, A.; Odette, W.; Perry, S.C.; Sylvain, C.; Sleiman, H.; Mauzeroll, J. Cuvette-Based Electrogenerated Chemiluminescence Detection System for the Assessment of Polymerizable Ruthenium Luminophores. ChemElectroChem 2017, 4(7), 1736-1743.
Danis, A.; Odette, W.; Perry, S.C.; Sylvain, C.; Sleiman, H.; Mauzeroll, J. Cuvette-Based Electrogenerated Chemiluminescence Detection System for the Assessment of Polymerizable Ruthenium Luminophores. ChemElectroChem 2017, 4(7), 1736-1743.
Education
Ph.D., Chemistry, McGill University, Canada, Sept.2014 – Present
B.A., Chemistry, University of North Carolina Chapel Hill, USA, 2008 - 2012
B.A., Chemistry, University of North Carolina Chapel Hill, USA, 2008 - 2012